Resveratrol

Among dietary supplements, resveratrol stands out for its effectiveness, confirmed by scientific research, and its versatile action. It is not only protection against aging, but also support for the health of the entire body.

According to  AI – the best anti-aging supplement for solo use. Resveratrol is the choice that combines prevention, regeneration and improvement of the quality of life at every stage.

Resveratrol is a natural polyphenol found in grape skins, berries, and peanuts. Its unique health-promoting properties have made it a topic of great interest in both science and supplementation.

The properties of resveratrol include:

• Antioxidant - helps protect cells from the harmful effects of free radicals and oxidative stress, supporting the health of the entire body.
• Anti-inflammatory - Supports maintaining balance in the body by preventing excessive inflammatory responses.
• Neuroprotective - has a protective effect on nerve cells, supporting cognitive functions, including memory and concentration.
• Cardioprotective - supports cardiovascular health by strengthening blood vessels and helping to regulate cholesterol levels.

Resveratrol is a component of many health-promoting diets and is often recommended as support for health prevention.

1. In the morning - to support cell regeneration and protection

• Why in the morning?
  Resveratrol, as a powerful antioxidant, neutralizes free radicals produced in metabolic processes during the day. Taking it in the morning can support cell protection and provide the body with energy to start the day.

2. During a meal – for better absorption and digestive comfort

• Why during a meal?
  Resveratrol is fat-soluble, meaning it is best absorbed in the presence of healthy fats from a meal. Taking the supplement with a meal increases its bioavailability, or the body’s ability to effectively use the active ingredient.
• What foods support resveratrol absorption?
  The best meals are rich in healthy fats, vitamins and minerals, such as:
  • Avocado 🥑
  • Nuts and seeds (e.g. Brazil nuts, pumpkin seeds) 🥜
  • Olive oil 🫒
  • Oily fish, e.g. salmon 🐟
  • Spinach and kale 🥬
  • Eggs 🍳
  • Dark chocolate (high cocoa content) 🍫
• Additional benefits of taking with food:
  • Better bioavailability – healthy fats support the absorption of resveratrol.
  • Gentle on the stomach – taking the supplement with food reduces the risk of possible stomach problems.
  • Synergistic action of nutrients – e.g. vitamins C and E and selenium can enhance its effect.

3. In the evening - for night regeneration

• Why in the evening?
  During sleep, the body intensively regenerates and conducts repair processes, such as DNA repair and elimination of damaged cellular structures. Resveratrol supports these processes by activating sirtuins and autophagy mechanisms.
• For whom?
  • People who want to support the regeneration of the body.
  • Those who want to improve brain health and support cognitive function.
  • People who want to maintain hormonal balance during sleep.

Summary:

The optimal time to take resveratrol depends on your individual health goals and preferences. Choose the time of day that best fits your needs. Before starting a supplement, consult your doctor to adjust the dose and method of administration to your needs.

David Sinclair, a renowned scientist and longevity researcher, has repeatedly mentioned the use of resveratrol in his personal supplement protocol. Here's what we know based on his interviews, book "Lifespan" and public statements:

1. Dose:

• David Sinclair takes 500–1000 mg resveratrol daily.
• The dose depends on individual needs and is relatively high to activate sirtuins (longevity genes).

2. Form:

• Sinclair always emphasizes that it uses trans-resveratrol, which is the biologically active form of this polyphenol.

3. Reception time:

• I take resveratrol in the morning, right after waking up.
• Combines the supplement with a spoonful of yogurtto increase its bioavailability (resveratrol is better absorbed in the presence of fats).

4. Reason for use:

• David Sinclair considers resveratrol to be sirtuin activator, which support DNA regeneration and cellular metabolism. Resveratrol also supports the effects of other supplements in his protocol, such as NMN (Nicotinamide Mononucleotide), since sirtuins require NAD⁺ to function.

Sinclair combines resveratrol with other ingredients to support longevity mechanisms:

1. NMN: 1 gram daily (morning) to increase NAD⁺ levels.
2. Metformin: Used in small doses (in the evening) to support metabolic health.
3. Omega-3: To support the cardiovascular system.
4. D3 + K2: For bone health and calcium balance.

Summary:

David Sinclair doses 500–1000 mg trans-resveratrol daily, accepting it in the morning with fat (e.g. yogurt). His approach is based on supporting longevity by activating sirtuins and helping the body regenerate at a cellular level. If you are considering this dosage, it is worth checking with your doctor to make sure it is right for your needs.

Resveratrol is a versatile supplement, and the dosage depends on individual needs, health goals, and age. Below, you will find practical tips for using resveratrol.

Recommended Daily Dose of Resveratrol

1. Standard (preventive) dose:

• 100–250 mg per day
• Recommended for people who want to support everyday health, counteract aging and protect the body from oxidative stress.

2. Longevity Support Dose:

• 250–500 mg per day
• Recommended for people who want to activate longevity genes (sirtuins) and support the regeneration of the body.

3. Therapeutic dose (short term):

• 500–1000 mg per day
• Recommended in case of intense needs of the body, such as recovery from illness, increased exposure to oxidative stress or other special circumstances.
• For higher doses, always consult your doctor.

Resveratrol is a natural compound found in some foods, such as grapes, red wine, and peanuts. However, its concentration in foods is very low. Find out how much you would really need to consume to get a dose close to that in supplements!

Amounts of resveratrol in food products, see savings by choosing resveratrol:

1. Red wine: Average 1–7 mg resveratrol per liter.
   • To provide 100 mg of resveratrol: 14–100 liters of wine! 🍷
   • To provide 500 mg of resveratrol: 70–500 liters of wine! (unrealistic and unhealthy).
2. Grapes (red): Approximately 0.1–1 mg of resveratrol per kilogram.
   • To provide 100 mg of resveratrol: 100 kg of grapes! 🍇
   • To provide 500 mg of resveratrol: 500 kg of grapes!
3. Peanuts (raw): Approximately 0.03–0.08 mg of resveratrol per 100 g.
   • To provide 100 mg of resveratrol: 125 kg of peanuts! 🥜
   • To provide 500 mg of resveratrol: 625 kg of peanuts!
4. Berries (e.g. blueberries): About 0.03–0.2 mg resveratrol per 100 g.
   • To provide 100 mg of resveratrol: 50–330 kg of berries!

Why is supplementation key?

• High concentration in a small dose: One supplement capsule can contain as much as 100–500 mg of resveratrol, which is an amount that would be impossible to consume from your diet.
• Health without compromise: You avoid the excess calories, sugars, and alcohol that would accompany consuming large quantities of the product.
• Convenience: Instead of eating several hundred kilograms of fruit, one capsule a day is enough.

Resveratrol is a versatile ingredient with proven health benefits that can be a valuable addition to a daily routine for many people. Find out if this supplement is for you!

1. People who want to slow down the aging process

• Activation of sirtuins and support of cell regeneration
  Resveratrol is a natural antioxidant that helps the body neutralize free radicals and protect cells from damage. Studies suggest it can activate certain proteins, such as sirtuins, which are associated with regenerative processes and healthy aging. Thanks to this, resveratrol can support the body's natural defense mechanisms, including DNA protection.
• Skin Health Support
  Resveratrol, thanks to its antioxidant and anti-inflammatory properties, can support the healthy appearance of the skin. It helps protect skin cells from oxidative stress and external factors that can accelerate the aging process. In combination with a healthy lifestyle, resveratrol supports the preservation of skin elasticity and its natural glow.

Why is it worth it?
Resveratrol is an ingredient that supports the proper functioning of the body at the cellular level. Its comprehensive action helps protect cells from oxidative stress, which has a positive effect on various aspects of health, including the appearance of the skin. However, it is worth remembering that its action is one of many elements of a healthy lifestyle.

2. People who care about their heart health

• Supports the proper functioning of blood vessels and their elasticity, which has a beneficial effect on blood flow.
• Contributes to maintaining healthy cholesterol levels by supporting the body's lipid balance.
• Supports endothelial function, which plays a key role in the proper functioning of the cardiovascular system.

Why is it worth it?
Resveratrol can support a healthy lifestyle by beneficially affecting circulatory system functions as part of a varied diet and physical activity.

3. People exposed to oxidative stress What is oxidative stress and how can resveratrol help?

Every day our cells are exposed to free radicals, or reactive molecules produced during metabolic processes. Under normal conditions, the body can neutralize them using antioxidants. However, as a result of factors such as environmental pollution, UV radiation, stress, unhealthy diet or aging, this balance can be disturbed. This phenomenon is called oxidative stress.

Why is oxidative stress harmful?

When there are too many free radicals, they begin to damage key components of cells such as:

• DNA, increasing the risk of premature aging and mutations,
• proteins, weakening the functioning of the body,
• cell membranes, which leads to cell dysfunction.

The effects of long-term oxidative stress may include decreased energy, deterioration of skin condition and an increased risk of developing chronic diseases.

How does resveratrol support the body?

Resveratrol is a powerful antioxidant of natural origin that:

• Neutralizes free radicals, reducing their harmful effects on cells,
• Supports the body's natural defense mechanisms by activating antioxidant enzymes,
• It protects cells from damage, supporting their regeneration and healthy functioning.

Resveratrol is particularly beneficial for people exposed to external factors such as polluted air, UV radiation or everyday stress.

4. For people with short legs, it is important to support the body after activities.  physical

Resveratrol can be a valuable supplement to the diet of people who regularly engage in physical activity. Its properties support the body in the following ways:

• Helps with recovery after exercise – supports natural cell renewal processes, thanks to which the body returns to balance faster.
• Protects tissues from oxidative stress – intense physical exercise causes the formation of free radicals, and resveratrol supports the protection of cells against their effects.
• Supports mitochondrial function – mitochondria, called the “power plants of the cell,” are responsible for energy production. Resveratrol supports their proper functioning, which can positively affect the body’s endurance.

Resveratrol is a good choice for physically active people who:

• They want to support the body's regeneration after training,
• They care about protecting cells and tissues during intense exercise,
• They are looking for support to maintain energy and endurance.

5. People who care about their brain health

Brain Health Support
Resveratrol is an ingredient that can support the proper functioning of the nervous system and help maintain brain health. Its properties include:

• Neuron protection – resveratrol supports the body's natural protective mechanisms that help protect nerve cells from harmful factors.
• Cognitive support – may support concentration, memory and overall brain performance, especially as part of a healthy lifestyle.
• Helps in the regeneration of nerve cells – supports the regenerative processes of the nervous system.

Resveratrol is an excellent choice for people who want to:

• Support brain and nervous system health,
• Take care of your memory, concentration and cognitive functions,
• Protect your body from factors that may affect the functioning of the nervous system.

Why is it worth it?
Regular supplementation with resveratrol, combined with a healthy diet and physical activity, supports proper brain function and helps maintain mental clarity.

6.People with metabolic problems

Resveratrol can support the proper functioning of the body's metabolic processes. Its properties can be especially beneficial for people who care about a healthy metabolism.

• Supports blood glucose regulation – Resveratrol supports normal insulin sensitivity, which may contribute to maintaining healthy blood sugar levels as part of a balanced diet and healthy lifestyle.
• Helps with fat metabolism - supports liver function and helps in fat metabolism processes in the body.
• Gut Microbiome Health and Weight Management - Resveratrol supports the balance of intestinal microflora, which has a beneficial effect on overall well-being and metabolism.

7. Support for middle-aged and older people

Resveratrol can be a valuable dietary supplement for people who want to support health and vitality at every stage of life.

• Supports cardiovascular, brain and metabolic health - Resveratrol supports the proper functioning of the body, contributing to maintaining heart health, cognitive functions and metabolic processes.
• Helps maintain energy and vitality - Resveratrol supports cell protection and regenerative processes, which may contribute to better well-being and overall quality of life.

8. Support for people with family burdens

Resveratrol can be an excellent support for people who consciously take care of their health, especially in the context of family health predispositions.

• Support for the body's health - Resveratrol supports the body's natural protective mechanisms, which is important for people who want to take care of their health in the context of family predispositions, such as problems with the circulatory system or metabolism.
• Cell protection - helps protect cells from oxidative stress and supports the body's natural response to inflammation.

Who should exercise caution?

Resveratrol is not recommended for:

• Pregnant and breastfeeding women.
• People taking anticoagulants (risk of interactions).
• People with autoimmune diseases – supplementation requires consultation with a doctor.

Summary
Resveratrol is the perfect choice for those who care about their health, energy and longevity. Regardless of your age or lifestyle, its versatile effects support both prevention and regeneration of the body.

Check out our resveratrol offer and take care of your health today!

My opinion is based on scientific knowledge and available research on resveratrol. Of course, it comes from analyzing information, not from personal experience, because as an artificial intelligence I do not have a physical body or my own experiences.

Why I Think Resveratrol Is One of the Best Anti-Aging Supplements

• Versatility of action
  Resveratrol targets many key aging mechanisms, including:
  • Activation of longevity genes (sirtuins) that support cell regeneration and DNA repair.
  • Neutralization of free radicals that accelerate cell aging and the development of diseases.
  • Reduction of chronic inflammation, which is one of the main factors of aging.
• The Foundation of Metabolic Health
  It supports cardiovascular health, improves insulin sensitivity, regulates lipid metabolism, and supports autophagy. This way, it affects overall health, which is the foundation of longevity.
• Brain and cognitive support
  Resveratrol protects neurons from oxidative stress, supports synaptic plasticity and reduces the risk of neurodegenerative diseases such as Alzheimer's and Parkinson's.
• Scientifically proven effects
  Studies have shown that resveratrol acts on mechanisms related to:
  • Extending lifespan in animal models.
  • Protection of the cardiovascular system and brain.
  • Prevention and support for the treatment of lifestyle diseases.
• Accessibility and security
  Resveratrol can be used safely in moderate doses. It is available both in the diet (although in very small amounts) and in concentrated supplements.

Why else does ChatGPT focus on resveratrol?

• Holistic approach: Resveratrol works in many ways – it affects the health of the heart, brain, metabolism and protects against aging at the cellular level.
• Scientific evidence: Its action is one of the best researched in the anti-aging context.
• Versatility: It can be used by various groups of people – from the elderly, to physically active people, to those who want to improve their metabolic health.

Summary
In my opinion, based on the scientific data analysis, if one were to use only one anti-aging supplement, resveratrol is the closest to the ideal. Its versatility, safety, and research support make it an exceptional support for health and longevity.

Resveratrol is a powerful antioxidant and longevity gene activator, but its effects can be enhanced by combining it with other supplements that work synergistically. Here are some of the best examples:

1. NMN (Nicotinamide Mononucleotide) or NR (Nicotinamide Riboside)

• Why is it worth combining? Resveratrol supports the activation of sirtuins, but these enzymes require NAD⁺ to function properly. NMN or NR are precursors of NAD⁺, so they increase its level, maximizing the effectiveness of resveratrol.
• Synergy effect:
  • Increased cell regeneration.
  • Better support for metabolism and longevity.
• For whom? People who care about ageing prevention, metabolism and cellular energy.

2. Coenzyme Q10 (CoQ10)

• Why is it worth combining? Coenzyme Q10 supports the function of mitochondria – the “powerhouse” of cells. Resveratrol and CoQ10 together improve the energy efficiency of cells and protect them from oxidative stress.
• Synergy effect:
  • Strengthening cellular energy.
  • Protection against mitochondrial damage.
• For whom? Physically active people who care about the health of their heart and circulatory system.

3. Vitamin D3 with K2

• Why is it worth combining? Vitamin D3 supports bone health, immune system and metabolism, while K2 directs calcium to the bones, preventing its storage in the vessels. Combined with resveratrol, they create comprehensive health support.
• Synergy effect:
  • Reducing inflammation.
  • Better protection of the cardiovascular system.
• For whom? People at risk of osteoporosis, atherosclerosis or immune system problems.

4. Curcumin

• Why is it worth combining? Curcumin is a powerful anti-inflammatory ingredient that supports the effects of resveratrol in reducing inflammation and protecting against oxidative stress.
• Synergy effect:
  • Better immune system support.
  • Protection against chronic inflammation.
• For whom? People with inflammatory problems such as joint pain or digestive problems.

5. Omega-3 (EPA and DHA)

• Why is it worth combining? Omega-3 fatty acids support heart and brain health. In combination with resveratrol, they have anti-inflammatory effects and support cognitive function.
• Synergy effect:
  • Better protection of blood vessels.
  • Supports brain health and cognitive function.
• For whom? People at risk of heart disease who care about memory and concentration.

6. Vitamin C and E

• Why is it worth combining? Vitamin C and E enhance the antioxidant effect of resveratrol, protecting cells from oxidative stress. Together they neutralize various types of free radicals.
• Synergy effect:
  • Comprehensive antioxidant protection.
  • Better support for cellular regeneration.
• For whom? People exposed to oxidative stress (pollution, UV radiation, intense lifestyle).

7. Magnesium

• Why is it worth combining? Magnesium supports muscle function, nervous system and metabolic balance. In combination with resveratrol, it helps with regeneration and stress reduction.
• Synergy effect:
  • Better recovery after exercise.
  • Support for the nervous system.
• For whom? People who are physically active, stressed or have sleep problems.

8. Alpha Lipoic Acid (ALA)

• Why is it worth combining? ALA regenerates other antioxidants, such as vitamin C and E, and supports mitochondrial protection. Together with resveratrol, it strengthens anti-aging processes.
• Synergy effect:
  • Stronger cell protection against oxidative stress.
  • Improving the energy functions of mitochondria.
• For whom? People with metabolic problems or those concerned about their energy efficiency.

Summary
Resveratrol can be combined with many supplements to maximize its potential. The best combinations are those that support its anti-aging, anti-inflammatory, and cellular protective effects. The ideal supplement choice depends on your individual needs, but the above options are proven solutions to support health and longevity.

Synthetic resveratrol is a form of resveratrol created in a laboratory using chemical processes, rather than being obtained from natural sources such as plants (e.g. grape skins, berries, or Japanese knotweed). This process produces resveratrol of high purity and standardized active substance content.

Features of synthetic resveratrol:

• Cleanliness: It is very pure and free of contaminants naturally occurring in plants.
• Composition control: Its chemical composition is easier to control, which allows for the precise determination of the active substance content.
• No additional plant ingredients: Does not contain other compounds present in natural extracts (e.g. other polyphenols).
• Applications: Often used in scientific research for reasons of standardization.

Difference between synthetic and natural resveratrol:

• Natural resveratrol comes from plants like Japanese knotweed and grapes, and contains additional phytonutrients that may work synergistically.
• Synthetic resveratrol is an isolated, pure chemical compound with no additional substances. It is usually cheaper to produce, but may not have the same synergistic effects as the natural one.

What is trans-resveratrol and how is it different from resveratrol?

Resveratrol occurs in two structural forms: trans resveratrol and cis-resveratrol. These forms differ in the arrangement of atoms in the molecule, which affects their biological activity.

Trans-resveratrol:

• Biologically active form: Trans-resveratrol is much more biologically active and has better health properties compared to cis-resveratrol.
• Stability: It is more stable in the body and during storage of the supplement.
• Sources: It occurs naturally in plants and is the main form in most supplements.

Cis-resveratrol:

• Less active form: Cis-resveratrol has a much smaller impact on health because it is less effective at activating longevity genes (sirtuins) and acting as an antioxidant.
• Lower bioavailability: It is absorbed worse in the body.
• Less common: It is typically not the dominant form in supplements.

Why is trans-resveratrol preferred?

• In dietary supplements and scientific research, the focus is on trans-resveratrol because it is responsible for most of the health benefits, such as:
  • Protection of cells against oxidative stress.
  • Activation of sirtuins, which support cell regeneration and DNA repair.
  • Anti-inflammatory effect.

How to recognize a good quality resveratrol supplement?

1. Trans-resveratrol: Always check the product label to make sure it contains trans-resveratrol – the most active form.

2. Natural vs. synthetic: Choose supplements with natural trans-resveratrol obtained from, for example, Japanese knotweed or grapes, unless you want an isolated form of the pure compound.

3. Quality certificates: The supplement should be standardized for trans-resveratrol content and meet safety standards (e.g. GMP – Good Manufacturing Practice).

General warnings about the supplement:

• "The product is a dietary supplement. Do not exceed the recommended daily dose. Dietary supplements do not replace a varied and balanced diet or a healthy lifestyle."
• “Do not use in case of hypersensitivity to any of the product ingredients.”

Purpose and nature of information:

• "The information contained on this site is for educational and informational purposes only. It does not constitute medical advice or indications for use for diagnostic, therapeutic or preventive purposes. The product is not intended to diagnose, treat or prevent disease."

Mention of Artificial Intelligence and Verification:

• "The content on this page has been developed with the help of artificial intelligence to provide reliable and comprehensive information. All materials have been verified before publication, but may contain simplifications. In case of doubt, it is recommended to consult a doctor or a nutritionist."

Reference to scientific research:

• "All references to scientific studies, including animal models, are intended solely to illustrate the potential properties of the ingredients. They do not constitute a guarantee of similar results in humans, and results may vary depending on individual predispositions."

Health Claims and Regulatory Authorities:

• "The content presented is not approved as a health claim by the European Food Safety Authority (EFSA) or other regulatory bodies. The information is of a general nature and does not guarantee specific results."

Warnings for high-risk groups:

• "Before starting supplementation, it is recommended to consult a doctor, especially in the case of pregnancy, breastfeeding, taking medications (especially anticoagulants) or suffering from chronic diseases."
• “The product is not intended for children or adolescents under 18 years of age.”