In a world constantly searching for the fountain of youth, Dr. David Sinclair, a Harvard professor of genetics, is emerging as a standard-bearer for anti-aging research. His rigorous scientific research is unlocking the secrets of aging, and interestingly, he doesn’t just preach, he practices. Sinclair’s supplement regimen is a testament to his belief in the potential of certain compounds to slow the aging process. Let’s delve into the concoction of supplements he incorporates into his daily routine, with a disclaimer: the dosages mentioned are Sinclair’s own and may not be right for everyone.
Sinclair's Morning Ritual: NMN and Resveratrol
Every morning, Sinclair starts his day with a gram of nicotinamide mononucleotide (NMN) and resveratrol. NMN is a precursor to NAD+, a key molecule involved in the body’s energy metabolism, while resveratrol is known for its antioxidant properties. He mixes these compounds into yogurt to aid absorption.
His morning routine also includes a significant dose of vitamin D3, ranging from 4,000 to 5,000 IU, and vitamin K2. The exact dose of vitamin K2 he takes daily is not specified, but it is intended to support bone health and cardiovascular function.
Midday Supplements: Fisetin and Quercetin
As the day progresses, Sinclair incorporates more supplements into her diet. She takes 500 mg of fisetin and 500 mg of quercetin, both with yogurt, to potentially improve cell function and fight inflammation.
Evening essentials: Metformin, aspirin and TMG
In the evening, Sinclair’s routine includes metformin, a prescription drug known for its ability to control blood sugar. He takes 1 gram of metformin, divided into two 500-mg doses, one in the morning and one in the evening, except on days when he exercises. Other important items in his evening routine include low-dose aspirin (83 mg daily), aimed at cardiovascular health, and TMG (TriMethylGlycine), at a dose of 500 mg to 1,000 mg daily, thought to support liver function and cardiovascular health.
Contemplating the Future: Aging as a Controlled State
Sinclair’s supplement regimen reflects his deep understanding of the molecular mechanisms of aging. As he navigates the landscape of anti-aging research, his personal supplement regimen offers insight into a potential future where aging can be a manageable condition.